The DHEA-S test evaluates conditions associated with abnormal levels of this hormone. Elevated DHEA-S levels can indicate conditions such as adrenal hyperplasia or tumors, and may cause symptoms like excessive hair growth, acne, and menstrual irregularities. Low levels of DHEA-S may be related to adrenal insufficiency, resulting in symptoms such as fatigue, decreased libido, and muscle weakness. The test is useful in diagnosing and monitoring these conditions, as well as assessing overall adrenal health.